Substance: tamoxifen citrate
Trade Names:
Ceadon 10, 20 mg tab.; Beta Argentina
Crioxifeno 20 mg tab.; Cryo Pharma Mexico
Defarol 10 mg tab.; Proel GR
Dignotamoxi (o.c.) 10, 20, 30, 40 mg tab.; Dignos Chemie
G
Duratamoxifen 10, 20, 30 mg tab.; Durachemie G
Emblon 10, 20 mg tab.; Berk GB
Jenoxifen 10, 20, 30 mg tab.; Jenapharm G
Kessar 10, 20, 30, 40 mg tab.; Pharmacia G
Kessar 10, 20, 30, 40 mg tab.; Farmitalia A
Kessar 10, 20 mg tab.; Farmatalia 1; Farmitalia-Carlo
Erba CH, Fl, GR
Ledertam 10, 20 mg tab.; Teva S
Mandofen 10, 20, 30, 40 mg tab.; MW Pharma G
Mandofen 10 mg tab.; Pentafarma PL
Noltam 10, 20 mg tab.; Lederle GB
Nolvadex 10 mg tab.; Zeneca G, Mexico, GB ICI Pharma,
A, CH, B, DK, ES,
Nolvadex 20, 30, 40 mg tab.; Zeneca G ICI Pharma A,
CH, DK, FR, NL, S, Fl, ES,
Nolvadex D 20 mg tab.,- ICI B, ES, 1, PL, GB, GR
Nolvadex forte 40 mg tab.,- ICI GB, B
Noncarcinon 10 mg tab.,- Fidelis PL
Nourytarn 10, 20, 30, 40 mg tab.; Nourypharma G
Oxeprax 20 mg tab. - Wyeth-Orfi ES
Riboxifen (o.c.) 10, 20, 30, 40 mg tab.; Ribopharm.
G
Tadex 10 mg tab.; Atabay TK
Tadex 10, 20, 40 mg tab.; Lääkefarmos Fl
Tafoxen 10, 20 mg tab.; Ciba-Geigy NL
Tamax 10, 20, 40 mg tab.; Orion Corp. A
Tamaxin 10, 20, 40 mg tab.; Lääkefarmos S -, Orion DK
Tamcal 10, 20, 30, 40 mg tab.; Pharmacal F1
Tamexin 10, 20, 30, 40 mg tab.; Merckle FI
Tamifen 40 mg tab.; Medochemie BG
Tamofen 10, 20, 40 mg tab.; Leiras FI, Rhone-Poulenc
DK D, 5; Tillotts GB; Huh
Tamofene 10, 20 mg tab.; Roger Bellon FR
Tamoplex 10 mg tab.,- Conforma B; Er-Kim A
Tamoplex 30, 40 mg tab.; Chefifarm, GR
Tamoplex 10, 20, 30 mg tab.; Pharmachemie NL
Tamoxan 10, 20 mg tab.; Tecnimede PL; Kener Mexico
Tamoxasta 10, 20 mg tab.; Asta Medica G
Tamox-GRY 10, 20, 30, 40 mg tab.; GRY G
Tamoxifen 10, 20, 40 mg tab.; Farmitalia-Carlo Erba
GB; Generics S
Tamox. AL (o.c.) 10, 20 mg tab.; Aluid G
T cell pharm 10, 20, 30, 40 mg tab.; Cell pharm G
T citrate 10, 20 mg tab.; Chefifarm GR
Tamox. ct (o.c.) 10, 20, 30, 40 mg tab.; CT Arzneimittel
G
T dumex 10, 20, 30, 40 mg tab.; Dumex NL
Tamoxifen Ebewe 10, 20 mg tab.; Ebewe A
F Farmos CH 10, 20, 40 mg tab.; Bristol-Myers CH; Orion
T Fermenta 10, 20, 30, 40 mg tab. Fermenta 5
lamoxifen Hexal 10, 20, 30 mg tab.; Durascan DK
T Hexal (o.c.) 10, 20, 30, 40 mg tab.; Hexal G
T Heumann 10, 20, 30, 40 mg tab.; Heumann G
T Lachema 10 mg tab.; CZ
Tamoxifen Leiras 10 mg tab.; Leiras BG
Tamoxifen lederle 10, 20, 40 mg tab.; Lederle NL
Tamoxifen medac 10, 20, 30, 40 mg tab.,- Medac G
Tamoxifen mp 10, 20 mg tab. - MP LN
Tamoxifen NM 10, 20,40 mg tab. NM Pharma S
Tamoxifen NM 10, 20, 30, 40 mg tab., Generics DK
T Onkolan 10, 2 0, 3 0, 40 mg tab.; Lannacher Heilmittel
A
T. Pan Medica 10 mg tab.-, Pan-Medica FR
Tpharbita 10, 20 mg tab.; Pharbita NL
T-ratiopharm (o.c.) 10, 20, 30, 40 mg tab.,- Ratiopharm
G
T Sopharma 10 mg tab. The Chem. Pharm. & Res. Inst.
Sofia BG
Tamoxifen Tabletts 10 mg tab. Bar Labs U.S.
Tamoxifeno 10 mg tab.,- Farmitalia- Carlo Erba ES
T Farmitalia 10, 20 mg tab.; Farmitalia ES
Tamoxifeno Funk 10, 20 mg tab. Funk S.A. ES
Tamoxifeno Septa 20 mg tab.; Septa ES
T Wassermann 10 mg tab. - Wassermann ES
Tamoxifenum 10, 20 mg tab.; Centrafarm NL
Tamoxifenum gf 10, 20, 40 mg tab.-, GF NL
Tamoxifenum pch 10, 20, 30, 40 mg tab.; PCH NL
Tamoxigenat (o.c.) 10, 20, 30, 40 mg tab.; Azuchemie
G
Tamox-Puren (o.c.) G 10, 20, 30, 40 mg tab.; Klinge-Nattermann-Puren
Taxus 20 mg tab.; Andromaco Mexico
Tecnofen 10, 20 mg tab.; tecnofarma Mexico
Zemide (o.c.) 10, 20, 30, 40 mg tab.; Wyeth-Pharma G
Zitazonium (o.c.) 10 mg tab.; Med Pharma G
Zitazonium 10 mg tab. -, Thiemann G; Egis HU,
This remedy is somewhat different from others since
it is not an anabolic/androgenic steroid. For male and
female bodybuilders, how-ever, it is a very useful and
recommended compound which is con-firmed by its widespread
use and mostly positive results. Nolvadex belongs to
the group of sex hormones and is a so-called antiestrogen.
The normal application of Nolvadex is in the treatment
of certain forms of breast cancer in female patients.
With Nolvadex it is pos-sible to reverse an existing
growth process of deceased tissue and prevent further
growth. The growth of certain tissues is stimulated
by the body's own estrogen hormone. This is especially
true for the breast glands in men and women since the
body has a large number of estrogen receptors at these
glands which can bond with the estro-gens present in
the blood. If the body's own estrogen level is unusu-ally
high an undesired growth of breast glands occurs. However,
in healthy women and particularly in men this is not
the case. Despite this, it is mostly male bodybuilders
who use Nolvadex, and fewer women. At first sight this
seems somewhat inconceivable but when taking a closer
look, the reasons are clear. Bodybuilders who take Nolvadex
also use anabolic steroids at the same time. Since most
steroids aromatize more or less strongly, i.e. part
of the substance is converted into estrogens, male bodybuilders
can experience a sig-nificant elevation in the normally
very low estrogen level. This can lead to feminization
symptoms such as gynecomastia (growth of breast glands),
increased fat deposits and higher water retention.
The antiestrogen Nolvadex works against this by blocking
the es-trogen receptors of the effected body tissue,
thereby inhibiting a bonding of estrogens and receptor.
It is, however, important to un-derstand that Nolvadex
does not prevent the aromatization but only acts as
an estrogen antagonist. This means that it does not
prevent testosterone and its synthetic derivatives (steroids)
from converting into estrogens but only fights with
them in a sort of "competition" for the estrogen
receptors. This characteristic has the disadvantage
that after the discontinuance of Nolvadex a "rebound
effect" can occur which means that the suddenly
freed estrogen receptors are now able to absorb the
estrogen present in the blood. For this reason the combined
intake of Proviron is suggested (see Proviron.) Nolvadex
is also useful during a diet since it helps in the burning
of fat. Al-though Nolvadex has no direct fatburning
effect its antiestrogenic effect contributes to keeping
the estrogen level as low as possible. Nolvadex should
especially be taken together with the strong an-drogenic
steroids Dianabol and Anadrol 50, and the various test-osterone
compounds. Athletes who have a tendency to retain water
and who have a mammary dysfunction should take Nolvadex
as a prevention during every steroid intake. Since Nolvadex
is very affective in most cases it is no wonder that
several athletes can take Anadrol 50 and Dianabol until
the day of a competition, and in combination with a
diuretic still appear totally ripped in the. limelight.
Those who already have a low body fat content will achieve
a visibly improved muscle hardness with Nolvadex.
Several bodybuilders like to use Nolvadex at the end
of a steroid cycle since it increases the body's own
testosterone production -which will be discussed in
more detail in the following-to counter-act the side
effects caused by the estrogens. These can occur after
the discontinuance of steroids when the androgen level
in relationship to the estrogen concentration is too
low and estrogen becomes the dominant hormone. A very
rare but all the more serious problem of Nolvadex is
that in some cases it does not lower the estrogen level
but can increase it. Another disadvantage is that it
can weaken the anabolic effect of some steroids. The
reason is that Nolvadex, as we know, reduces the estrogen
level. The fact is, however, that certain steroids -especially
the various testosterone compounds-can only achieve
their full effect if the estrogen level is sufficiently
high. Those who are used to the intake of larger amounts
of various steroids do not have to worry about this.
Athletes however, who predominantly use mild steroids
such as Primobolan, Winstrol, Oxandrolone, and Deca-Durabolin
should carefully consider whether or not they should
take Nolvadex since, due to the compound's already moderate
ana-bolic effect, an additional loss of effect could
take place, leading to unsatisfying results.
A rarely observed but welcome characteristic of Nolvadex
is that it has a direct influence on the hypothalamus
and thus, by an in-creased release of gonadotropine,
it stimulates the testosterone pro-duction in the testes.
This does not result in a tremendous but still a measurable
increase of the body's own testosterone. This effect,
however, is not sufficient to significantly increase
the testosterone production reduced by anabolic/androgenic
steroids.
The side effects of Nolvadex are usually low in dosages
of up to 30 mg/day In rare cases nausea, vomiting, hot
flashes, numbness, and blurred vision can occur. In
women irregular menstrual cycles can occur which manifest
themselves in weaker menstrual bleeding or even complete
missing of a period. Women should also be careful not
to get pregnant while taking Nolvadex. It is important
for fe-male athletes that Nolvadex and the "pill"
not be taken together since the antiestrogen Nolvadex
and the estrogen-containing pill nega-tively counterfeit
each other. The normal daily dosage taken by athletes
corresponds more or less to the dosage indications of
the manufacturer and is 10-30 mg/day To prevent estrogenic
side ef-fects normally 10 mg/day are sufficient, a dosage
which also keeps low the risk of reducing the effect
of simultaneously-taken ste-roids. Often it is sufficient
if the athlete begins this preventive intake of Nolvadex
only three to four weeks after the intake of anabolics.
Athletes who have tendencies toward gynecomastia, strong
water retention, and increased fat deposits with steroids
such as Dianabol, Testosterone, Anadrol 50, and Deca-Durabolin
usually take 20-30 mg/day The combined application of
Nolvadex 20-30 mg/day and Proviron 25-50 mg/day in these
cases leads to excellent results. The same is true for
athletes who are in competition, and for women. Women,
however, should do without the intake of Proviron or
at least reduce the dose to one 25 mg tablet per day.
Unfortunately, in most cases, a very pronounced gynecomastia
("bitch tits") cannot be reduced by taking
Nolvadex so that often surgery is required, surgery
which is not paid for by health insurance. First signs
of a possible gynecomastia are light pain when touching
the nipples. The tablets are usually taken 1-2x daily,
swallowed whole without chewing, with some liquid during
meals.
Nolvadex unfortunately is a very expensive compound.
Some ex-amples: In Germany one hundred 20 mg tablets
cost $192. In Spain the prices are fixed by the govern-ment
and it makes no difference whether it is an original
Nolvadex or a generic compound. One hundred 20 mg tablets
cost approx. $60 in Spain. In Greece the same quantity
costs about $85. The athlete should look for the 20-mg
version since, from its price, it is the most economical.
On the black-market, mostly the foreign Nolvadex can
be found costing about $2 - 3 per 20 mg tablet. Origi-nal
Nolvadex tablets can be easily identified since, on
the front, ICI (name of the manufacturer) is stamped
and, on the back, the name "Nolvadex". Most
of the time the tablet strength is also imprinted. Ten
tablets are included in an unusually large push-through
strip. In the U.S. original Nolvadex is packaged by
the manufacturer, ICI Pharma, in small, white plastic
boxes with a childproof screw cap. So far there are
no fakes of Nolvadex and its generic products.